1,300 BC to 1000 AD  - Olmecs occupy area around Tres Zapotes.

500-1000 Teotihuacan related peoples settle in area.
1465? - Aztec Motecuhzoma Ilhuicamina (1440-1469) conquers the south central Veracruz area.

1522 - Hernán Cortés arrives at Totógatl, forerunner of Santiago Tuxtla. (disputed)
1523 - First sugarcane planted near Uvero
1525 - Foundation of Santiago Tuxtla.
1529 - Hernán Cortés is awarded the area as part of the Marquesado del Valle de Oaxaca.
1523 - First sugarcane plantations in Los Tuxtlas

1530 - San Martin Volcano erupts. (disputed)
1580 - the
estancia of Santiago Tuxtla is mentioned
1664 - Volcano San Martin eruption evacuates many Santiago Tuxtla residents  to San Andres Tuxtla.

1718 - San Andres becomes a pueblo, separating it from Santiago.
1793 - San Martin Volcano erupts.

1825 - mentions Canton de Santiago Tuxtla as part of Acayucan.
1826 - San Andres Tuxtla secedes from Santiago Tuxtla.
1833 - Cholera wipes out half the population.
1950 - Santiago Tuxtlas receives the title "ciudad" (city)
1953 - The federal highway is paved.
1974 - The city is officially declared "Ciudad Colonial" (colonial city).
1979 - San Martin Volcano is declared a national reserve
1998 - The Biosphere Reserve of Los Tuxtlas is created
2008 - First modern bank opened.
History
DRAFT
Santiago Tuxtla
Veracruz, Mexico